February 9, 2026 2:31 am EST

Kaley Cuoco is getting candid about the aftermath of her 2022 divorce from Karl Cook.

“It was the premiere of the second season of Flight Attendant, and I woke up that morning, I was so depressed and so sad, I couldn’t even breathe and I was just laying on the floor. I literally thought I was gonna die. I really did. I said, ‘What am I doing?’” Cuoco, 40, said during a recent interview, which is set to air Monday, February 9, on The Drew Barrymore Show, per Entertainment Weekly.

Cuoco noted that the moment was “the worst morning” of her life, despite thinking the premiere of Flight Attendant — which was cancelled in 2024 after two seasons at Max — was “supposed to to be the best night.”

“It’s so crazy those things sometimes happen at the same time,” she said. “My team came over to get me ready, and they literally got me ready on the floor. I couldn’t get up. I’m like, ‘I can’t go. I can’t go anywhere. I blew up my life. My life’s over.’ I truly thought that. Never getting married again. I’m never gonna have kids. This is it.”

Related: Kaley Cuoco’s Dating History: Johnny Galecki, Karl Cook and More

From costar romances to divorces, Kaley Cuoco’s love life has been making headlines for years. Cuoco wed Ryan Sweeting in 2013, but the two called it quits after 21 months of marriage. Following the split, the actress went on to date Paul Blackthorne and Henry Cavill before wedding Karl Cook in 2018. Three years into […]

Cuoco continued, “I knew, when I was laying on that floor in my house, I thought, ‘Oh my God, this is what they talk about. This is the lowest point I could get.’”

Three weeks later, Cuoco met Tom Pelphrey. The pair, who are currently engaged, are parents to daughter Matila, 2.

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“I had prayed, and I feel like my soul died,” she said. I feel like my soul died, and I had also said — I think I did a magazine. It was like, ‘I’m never getting married again.’ I said it, I believed that in the moment, [and then] met Tom.”

In Cuoco’s perspective, it’s OK to change your opinion on marriage.

“Sometimes you just change your mind and that’s OK,” she said. “You probably didn’t know I was laying on the floor before my premiere ready to die, that’s true… It still chokes me up because I can remember it so clearly, but it made me a whole new person. But it takes a long time. It takes a long time to figure that out and a lot of forgiveness.”

Related: Kaley Cuoco and Ex Johnny Galecki’s Friendship Through the Years

No hard feelings! Kaley Cuoco and Johnny Galecki have maintained a strong friendship since their 2009 split — and never let their personal lives get in the way of their professional bond. The actors worked together on the Big Bang Theory for 12 seasons from 2007 to 2019. When the series began, they sparked an […]

Cuoco began dating Cook, now 35, in 2016 after a three-year marriage to tennis pro Ryan Sweeting. Cuoco and Cook tied the knot in 2018, announcing their separation three years later. The pair’s divorce was finalized in 2022. That same year, Cuoco confirmed she was dating Pelphrey, now 43.

While reflecting on his parenting with Cuoco, Pelphrey exclusively told Us Weekly last month that the Big Bang Theory actress is “great.”

“Thank god she’s there because we have a little girl, and she’s a daddy’s girl, and I have a hard time saying no to anything,” Pelphrey shared. “So we need Kaley to lay down the law.”

Pelphrey gushed that being a father and parenting with Cuoco is “literally the best part” of his life, adding, “Yeah, it rewires you. It just kind of happens. I feel everything’s different — the priorities are different.”

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