March 23, 2026 11:36 am EDT

Carrie Anne Fleming, best known for her roles in TV shows Supernatural and iZombie, has died.

Fleming’s rep confirmed her death, which occurred on February 26, via a statement shared with Us Weekly on Sunday, March 22. She was 51 years old.

“Carrie passed away a few weeks ago at the age of 51 due to cancer. She died peacefully with her loved ones by her side. She is survived by her daughter,” the statement read. “It was a great privilege to have known Carrie. She was a beautiful soul, inspiring, and above all, kind. She will be greatly missed.”

Supernatural star Jim Beaver, who played Bobby Singer opposite Fleming’s Karen Singer on the CW fantasy-drama series, took to Facebook on March 1 to reflect on the friendship he formed with his onscreen wife. His post also commented on Fleming’s battle with cancer — the same disease that killed his late wife, Cecily Adams, who died at the age of 46 more than two decades ago.

“I lost Cecily to cancer in 2004 … I lost Carrie to the same disease,” Beaver, 75, wrote alongside several photos of himself with Fleming. “I never thought my heart could break so badly more than once. But it has. But, oh, the two torches I carry. What bright, bright light they shed.”

Fleming appeared as Karen Singer during Supernatural seasons 5 and 7. Previously, she starred as Candy on CW’s iZombie from 2015 to 2019.

Per Beaver’s Facebook post, Fleming was instantly likeable when she joined Supernatural’s set in Canada, where Fleming lived, during season 5. “Carrie Anne Fleming was cast as my wife on Supernatural in my fifth season on the show. I fell for her hard, and I did it mere seconds after meeting her. To my joy and shock, it seems the same thing happened to her. We “met cute,” in Hollywood speak,” he wrote.

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The post continued, “As we sat on the set before our first scene, saying our hellos and breaking the ice as actors do when first paired up for a scene, she mentioned the name Madeline Rose. I was flummoxed, because that is my daughter’s name, and there was no reason Carrie should know it. I said tentatively, ‘Who’s Madeline Rose?’ She said, ‘Oh, that’s my daughter.’ I said, ‘Wait. That’s my daughter.’ Turns out that, spelling differences aside, our daughters had the same name. And that, as also happens in the movies, was the beginning of a beautiful friendship.”

Beaver also reflected on his former costar’s many charms. “She was a powerhouse of vitality and goodwill and amazingly good nature, with a rapturous laugh and an utterly adorable personality that didn’t seem to have an off switch,” he detailed.

Fleming’s work extended to film too, with appearances in 2007’s Good Luck Chuck, In the Name of the King: A Dungeon Siege Tale, Crossroads: A Story of Forgiveness, and Married Life, plus 2012’s The Christmas Consultant, and 2014’s TV movie Along Came a Nanny.

Per The Hollywood Reporter, she also gave an uncredited performance in 1996’s Happy Gilmore.

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