August 17, 2026 6:55 pm EDT

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So, you’re noticing your skin feels a little drier, fine lines are becoming more visible and despite sticking to the same skincare routine, your face has lost some of its usual bounce. If all that sounds familiar, hormones could be at play. As estrogen levels decline with age, skin can become drier, thinner and less elastic, which may explain why products that once worked perfectly no longer deliver the same results.

While many over-the-counter products address common changes in aging skin, Musely is a telehealth platform that connects patients with board-certified dermatologists and OB-GYNs for personalized, prescription-based care. Specifically, the brand’s Aging Repair Cream is a prescription-strength, custom-compounded formula made to target visible signs of hormonal skin aging.

Get The Anti-Aging Cream for $35 at Musely!

The star ingredient? Estriol, a bioidentical form of estrogen that helps support collagen production, moisture retention and elasticity as estrogen levels drop. Paired with other familiar skincare heavy hitters, including vitamin C, hyaluronic acid and aloe, it addresses multiple signs of aging in one step. With consistent use, that may translate to skin that looks more hydrated, plump and firm, with improvements in the appearance of fine lines, texture and overall elasticity in around six to eight weeks.

For those more focused on the symptoms of perimenopause and menopause, Musely also offers The Estrogen Cream, a topical hormone treatment for the body that combines estriol, estradiol and progesterone, offering an alternative for those who prefer a cream over a daily pill or patch. The formula is designed to help relieve common hormone-related symptoms like hot flashes, night sweats, mood changes and vaginal dryness. According to the brand, most women may begin noticing symptom relief within two to six weeks, with benefits continuing over several months as hormone levels stabilize.

Unlike traditional over-the-counter skincare, these formulas are prescription-only and require a provider review to determine if it’s appropriate for you. Musely makes the process surprisingly convenient: you’ll complete a three-minute online medical visit, and a provider will review the information. If prescribed, they custom-compound the formula for you.

Right now, new patients can also save 10% on their first order with the code WELCOME10.

Get The Anti-Aging Cream for $35 at Musely!

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